From Wikipedia,
the free encyclopedia
An active chromatin sequence
(ACS) is a region of DNA in a
eukaryotic chromosome in which
histone modifications such as
acetylation lead to exposure
of the DNA sequence thus allowing
binding of transcription factors
and
transcription to take place.
ACSs may occur in non-expressed
gene regions which are assumed to
be "poised" for transcription.
See also
Chromatin
References
[Genome-wide
identification of DNaseI
hypersensitive sites using active
chromatin sequence libraries]
